| 1954 |
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First successful kidney transplant performed. |
| 1966 |
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First simultaneous kidney/pancreas transplant performed. |
| 1967 |
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First successful liver transplant performed. |
| 1968 |
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First successful isolated pancreas transplant performed. First successful heart transplant performed. |
| 1981 |
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First successful heart-lung transplant performed. |
| 1983 |
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First successful single-lung transplant performed. Cyclosporine introduced. |
| 1984 |
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National Organ Transplant Act (NOTA) passed. |
| 1986 |
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First successful double-lung transplant performed. |
| 1987 |
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First successful intestinal transplant performed. |
| 1988 |
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First split-liver transplant performed. |
| 1989 |
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First successful living donor liver transplant performed. |
| 1990 |
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First successful living donor lung transplant performed. |
| 1998 |
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First successful adult-to-adult living donor liver transplant performed. |
| 2000 |
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U.S. Department of Health and Human Services publishes Final Rule (federal regulation) for the operation of the OPTN. |
| 2001 |
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For the first time, the total of living organ donors for the year (6,528) exceeds the number of deceased organ donors (6,081). |
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